==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 159
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1400Th1064MuromonabHeavy Chain: QVQLQQS Full view664IIaImmunologicalORTHOCLONE OKT3 STERILE SOLUTIONCentocor Ortho Biotech, L.P.Sterile Solution is a murine monoclonal antibody to the CD3 antigen of human T cells which functions as an immunosuppressant.For Intravenous Use OnlyImmunologic Factors and Immunosuppressive Agents N.A.
1406Th1066IbritumomabHeavy Chain: QAYLQQS Full view652IIbCancerZevalinSpectrum PharmaceuticalsClear, colorless, sterile, pyrogen-free, preservative-free solution that may contain translucent particles.Intravenous infusionN.A. Digoxin
1412Th1068TositumomabHeavy Chain 1: QAYLQ Full view1351IIbCancerBexxarGalaxo Smith KlineSterile, pyrogen-free, clear to opalescent, colorless to slightly yellow, preservative-free solution Intravenous(IV) administrationN.A. Bacterial outer membrane,Lipoteichoic acid synthesis
1431Th1073AlemtuzumabHeavy Chain 1: QVQLQ Full view2839IIaCancerCAMPATHGenzyme CorporationSterile, clear, colorless, isotonic solution (pH 6.8-7.4)Intravenous infusionN.A. N.A.
1432Th1073AlemtuzumabHeavy Chain 1: QVQLQ Full view2389IIaCancerLEMTRADAGenzyme CorporationLEMTRADA is a sterile, clear and colorless to slightly yellow, solution (pH 7.2±0.2) for infusion.Intravenous infusionNA NA
1434Th1074AlgluceraseARPCIPKSFGYSSVVCVCNA Full view497IaMetabolicCeredaseGenzyme CorporationClear sterile non-pyrogenic solution of alglucerase in a citrate buffered solutionIntravenous injectionEnzyme Replacement Agents Plasminogen,Proteinase-activated receptor 1
1435Th1075CapromabN.A. Full view0IVCancerProstaScintJazz Pharmaceuticals, Inc.Sterile, pyrogen-free, clear, colorless solution that may contain some translucent particles.Intravenous injectionIndicators, Reagents and Diagnostic Agents CAMPATH-1 antigen,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1437Th1076LaronidaseAPHLVQVDAARALWPLRRFW Full view626IaMetabolicALDURAZYMEGenzyme CorporationSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted prior to administration in 0.9% Sodium Chloride InjectionIntravenous infusionEnzyme Replacement Agents N.A.
1456Th1086Interferon Alfa-2B, RecombinantCDLPQTHSLGSRRTLMLLAQ Full view165IbImmunologicalINTRON® AMerckPowder or solutionIntramuscular, Subcutaneous, Intralesional, or Intravenous injectionImmunosuppressive Agents Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin
1460Th1087OxytocinCYIQNCPLG
Full view		9IbHormonalPitocinJHP PharmaceuticalsSterile, clear, colorless aqueous solution of synthetic oxytocinIntravenous infusionOxytocics, Anti-tocolytic Agents and Labor Induction Agents Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Globotriaosylceramide
1465Th1089PalivizumabVH region: QVTLRESG< Full view120IIIaInfectiousSynagisMedImmuneSterile, preservative-free liquid solutionIntramuscular injectionAntiviral Agents N.A.
1468Th1091BevacizumabDIQMTQSPSSLSASVGDRVT Full view214IIaCardiacAvastinGenentechSlightly opalescent, colorless to pale brown, sterile, pH 6.2 solution for intravenous infusionIntravenous infusionAngiogenesis Inhibitors Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1473Th1093EculizumabN.A. Full view0IaHaemetologicalSolirisAlexion, IncSterile, clear, colorless, preservative-free 10 mg/mL solution for intravenous infusionN.A.N.A. Complement C5
1475Th1095RanibizumabLight Chain SASQDISN Full view447IIaHematological/Eye DisorderLucentisGenentechSterile, colorless to pale yellow solutionIntravitreal injectionOphthalmics Vascular endothelial growth factor A
1476Th1096IdursulfaseSETQANSTTDALNVLLIIVD Full view525IaMetabolicElapraseSHIRESterile, nonpyrogenic clear to slightly opalescent, colorless solution that must be diluted prior to administration in 0.9% Sodium Chloride Injection, USPIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Heparan sulfate,Perilipin-3
1482Th1100PramlintideKCNTATCATQRLANFLVHSS Full view37IaHormonal/MetabolicSymlinAmylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca)Clear, isotonic, sterile solutionSubcutaneous injectionN.A. Calcitonin receptor,Receptor activity-modifying protein 1,Receptor activity-modifying protein 2,Receptor activity-modifying protein 3
1494Th1101GalsulfaseSGAGASRPPHLVFLLADDLG Full view497IaMetabolicNaglazymeBioMarinSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted with 0.9% Sodium Chloride Injection, USP, prior to administrationIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Perilipin-3
1502Th1105Insulin AspartA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicNovoLogNovo NordiskSterile, aqueous, clear, and colorless solutionSubcutaneous injection, Intravenous injectionHypoglycemic Agents and Antidiabetic Agents Insulin receptor
1511Th1106Insulin DetemirA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicLEVEMIRNovo NordiskClear, colorless, aqueous, neutral sterile solutionSubcutaneous injectionAntidiabetic Agents Insulin receptor
1520Th1107Insulin GlulisineA chain: GIVEQCCTSIC Full view51IbHormonal/MetabolicAPIDRAsanofi-aventisSterile, aqueous, clear, and colorless solutionN.A.Antidiabetic Agents Insulin receptor
1529Th1108PegaptanibN.A. Full view0IIaHematological/Eye DisorderMacugenGilead SciencesSterile, aqueous solution containing pegaptanib sodium for intravitreous injectionIntravitreal injectionIntended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. N.A.
1534Th1113Glatiramer AcetateEAYKAAEKAYAAKEAAKEAA Full view52IIaNeurological DisorderCopaxoneTeva Pharmaceutical IndustriesClear, colorless to slightly yellow, sterile, nonpyrogenic solutionSubcutaneous injectionN.A. N.A.
1548Th1117IpilimumabHeavy chain: QVQLVES Full view663IIIcCancerYERVOYBristol-Myers SquibbSterile, preservative-free, clear to slightly opalescent, colorless to pale-yellow solutionN.A.Antineoplastic Agents and Monoclonal antibodies Cytotoxic T-lymphocyte protein 4
1550Th1119TocilizumabN.A. Full view0IIaImmunologicalACTEMRAGenentechSterile, preservative-free solution, colorless to pale yellow liquid, with a pH of about 6.5Intravenous infusion, Subcutaneous injectionN.A. Interleukin-6 receptor subunit alpha
1556Th1120TeriparatideParathyroid hormone Full view34IbOsteologicalForteoEli Lilly and CompanySterile, colorless, clear, isotonic solutionSubcutaneous injectionBone Density Conservation Agents Parathyroid hormone/parathyroid hormone-related peptide receptor
1570Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalXgevaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1571Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalProliaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1576Th1124LiraglutideHAEGTFTSDVSSYLEGQAAK Full view33IbHormonalSaxendaNovo NordiskClear, colorless solutionSubcutaneous injectionN.A. Glucagon-like peptide 1 receptor
1577Th1124LiraglutideHAEGTFTSDVSSYLEGQAAK Full view33IbHormonalVictozaNovo NordiskClear, colorless solution.Subcutaneous injectionN.A. Glucagon-like peptide 1 receptor
1583Th1125GolimumabN.A. Full view0IIbImmunologicalSimponi InjectionN.A.Clear to slightly opalescent, colorless to light yellow solutionSubcutaneous injectionAntipsoriatic Agents and Monoclonal antibodies and TNF inhibitor Tumor necrosis factor
1584Th1125GolimumabN.A. Full view0IIbImmunologicalSimponi InjectionN.A.Sterile concentrated solution of the golimumab antibodyIntravenous infusionAntipsoriatic Agents and Monoclonal antibodies and TNF inhibitor Tumor necrosis factor
1600Th1127BuserelinN.A. Full view0IIIcCancer/HormonalSuprecur (Nasal Spray Solution)Sanofi-Aventis150 micrograms Nasal Spray SolutionNasal sprayN.A. Lutropin-choriogonadotropic hormone receptor,Gonadotropin-releasing hormone receptor
1615Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerEyleaRegeneron PharmaceuticalsSterile, clear, and colorless to pale yellow solution.Intravitreal injectionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1616Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerZaltrapSanofi and Regeneron Pharmaceuticals, Inc.Sterile, clear, colorless to pale yellow, non-pyrogenic, preservative-free, solution.Intravenous infusionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1622Th1135OcriplasminTruncated heavy chai Full view251IcEye DisorderJetreaThromboGenics NVSterile, clear and colorless solution with no preservativesIntravitreal injectionOphthalmics Fibronectin,Alpha-2-macroglobulin,Alpha-2-antiplasmin
1628Th1139Certolizumab PegolLight chain: DIQMTQS Full view443IIbImmunologcalCimziaUCBSterile, white, lyophilized powder for solution or as a sterile, solution in a single-use prefilled 1 mL glass syringeSubcutaneous injectionTNF inhibitor Tumor necrosis factor
1635Th1141Epoetin ZetaAPPRLICDSRVLERYLLEAK Full view166IbCancerRetacritNorbitecsolution for injectionN.A.N.A. Erythropoietin receptor
1654Th1150SecukinumabSecukinumab Heavy Ch Full view672IIaImmunologicalCosentyxNovartis Pharmaceuticals CorporationSterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution.Subcutaneous injectionInhibitor IL-17A cytokine
1667Th1158AprotininRPDFCLEPPYTGPCKARIIR Full view58IIaImmunologicalTrasylolBayer PharmaceuticalsClear, colorless, sterile isotonic solutionIntravenous administrationN.A. Trypsin-1, Chymotrypsinogen B, Plasminogen, Kallikrein-!
1674Th1161AlbiglutideHGEGTFTSDVSSYLEGQAAK Full view645IbHormonal disordersEperzanGlaxosmithkline IncPowder for SolutionSubcutaneousDrugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. Glucagon-like peptide 1 receptor
1676Th1161AlbiglutideHGEGTFTSDVSSYLEGQAAK Full view645IbHormonal disordersTanzeumGlaxo Smith Kline LlcInjection, Powder, Lyophilized, for SolutionSubcutaneousDrugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. Glucagon-like peptide 1 receptor
1678Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis U.S. LlcInjection, SolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 9
1679Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis Canada IncSolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 10
1680Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis Canada IncSolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 11
1681Th1162AlirocumabNA Full view0IcMetabolic/CardiacPraluentSanofi Aventis U.S. LlcInjection, SolutionSubcutaneousN.A. Proprotein convertase subtilisin/kexin type 14
1684Th1164Antithrombin AlfaNA Full view0IaHematological DisordersAtrynGtc Biotherapeutics, Inc.Injection, Powder, Lyophilized, for SolutionIntravenousNA NA
1685Th1164Antithrombin AlfaNA Full view0IaHematological DisordersAtrynR Evo Bioloigics, Inc.Injection, Powder, Lyophilized, for SolutionIntravenousNA NA
1688Th1165Antithrombin III humanNA Full view0IaHematological DisordersThrombate IIIGrifols Therapeutics IncPowder for SolutionNANA NA
1691Th1165Antithrombin III humanNA Full view0IaHematological DisordersThrombate III Pws IV 1000iu/vialMiles Inc. Pharmaceutical DivisionPowder for SolutionNANA NA
1694Th1166Asfotase AlfaLVPEKEKDPKYWRDQAQETL Full view726IaGenetic DisordersStrensiqAlexion Pharma GhbhSolutionSubcutaneousEnzymes Alimentary Tract and Metabolism Sphingosine 1-phosphate receptor 1; Pyrophosphate