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Details of SAPdb entry with Sequence L-Delta-F
Primary information
SAPdb ID 1291,
PMID22915849
Peptide NameLeucine-dehydroPhenylalanine (L-Delta-F)
Peptide sequenceL-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)
SolventMethanol and water (50:50; v/v).
MethodStock solutions were prepared by dissolving 2 mg of peptide in 50 μL of methanol, solution is sonicated to dissolve. Assembly was initiated by addition of 1 mL of aqueous methanol (50% v/v) to the stock. Samples were incubated for 24 hours.
Conc2mg/ml
TemperatureRoom temperature
Incubation Time24 hours
Year2012
Self assemblyYes
Type of Self assemblyFibrillar structures
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
Stable
Nanofiber
NA
IF
N.A.
Primary information
SAPdb ID 1492,
PMID22833945
Peptide NameLeu-alpha, beta-dehydroPhenylalanine
Peptide sequenceL-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide derivative
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
Solvent1,1,1,3,3,3-hexa-fluoro-isopropanol/water.
MethodStock solutions of dipeptides were prepared by dissolving 0.1–1 mg of them in 50 μl of HFIP. Solution heated and sonicated to dissolve the dipeptide. Assembly was initiated by addition of double-distilled water (1 ml) to the stock solution. Samples were aged 24–48 h before experiments.
Conc0.1 - 1mg/ml
TemperatureRoom temperature
Incubation Time24 -48 hours for sample aging and 30 - 60 minutes for self assembly
Year2010
Self assemblyYes
Type of Self assemblySmall micellar structure
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
Proteolytically stable
Other
NA
LF
N.A.
Primary information
SAPdb ID 1839,
PMID27507432
Peptide NameLeuΔPhe (Leucine-α, β-dehydroPhenylalanine)
Peptide sequenceL-Delta-F
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationDelta-F or Δphe=alpha-beta-dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
Conjugate partnerα,β-dehydrophenylalanine (ΔPhe)
TechniqueTEM, SEM, ESEM,CD and FTIR spectroscopy.
Solventsodium acetate buffer
Methodsolution phase peptide synthesis
Conc0.8 M
Temperature7
Temperature37 °C
Year2016
Self assemblyYes
Type of Self assemblyHydrogels
Tertiary Structure
(Technique)
Not Predicted),
Linear
NA
NA
Hydrogel
2000
LF
N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O