NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 2-alpha, 3-alpha, 19-beta, 23-beta-tetrahydroxyurs-12-en-28-oic acid

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCND1cyclin D1595-A2780----Consistent with its effect on apoptosis,THA induced changes in the expression of apoptosis related proteins in A2780. The expression of Cyclin-D1 was slightly decreased in a dose-dependent manner.21695177
CCND1cyclin D1595-HepG2----Consistent with its effect on apoptosis,THA induced changes in the expression of apoptosis related proteins in HepG2. The expression of Cyclin-D1 was slightly decreased in a dose-dependent manner.21695177

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.