NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

STATISTICS




1. General Information


Total No. of Compounds Total No. of Refrences Total No. of Cell Lines Total No. of Cancers Total No. Classes Compound-Cell Line Interactions Compound-target interaction
1574762353192752141980
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2. Comparision with other databases



The comparison with 3 other similar natural compound collections (HIT, Super Natural and Cancer Resource) with NPACT reveals that 880 compounds (56%) are unique. Individually we find that 1417,1390 and 1185 compounds are not found in HIT, Super Natural and Cancer Resource

    
DATABASESREDUNDANTUNIQUE
Super Natural Database 1841390
HIT1571417
Cancer Resource3891185
CTD663911
PubChem1297277










       
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3. Cancer-wise distribution of the compounds


       
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4. Cancer-wise distribution of Cell-lines


       
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5. Distribution of classes of compound


S No.ClassesNo. of Compounds
1Terpenoids 513
2Flavonoids 329
3Alkaloids 110
4Not Classified 35
5Polyketides 92
6Lignans 88
7Polycyclic aromatic natural products 63
8Steroids 80
9Simple aromatic natural products 82
10Saponin 51
11Carbohydrates 11
12Organic Chemicals 33
13Oxygen heterocycles 12
14Benzopyranoids 26
15Benzofuranoids 19
16Aliphatic natural products 20
17Aminoacids and peptides 3
18Polypyrroles 1
19Tannin 6



























       
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6. Distribution of Molecular Mass


       
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7. Distribution of Polar Surface Area


       

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8. Distribution of Hydrogen Donor


       

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9. Distribution of Hydrogen Acceptor


       

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10. Distribution of LogP


       

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11. Year-wise distribution of literature in NPACT


       
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12. Top 10 journals refered in NPACT

A total of 181 journals have been refered corresponding to 762 papers while creating NPACT. The distribution for top 10 journals which have conributed maximally in developing NPACT is shown.

       
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13. Top 15 targets present in NPACT


       


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14. Distribution of Suppliers

       


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15. Distribution of compounds per Cell line


S.No.Cell LinesCompoundsS.No.Cell LinesCompoundsS.No.Cell LinesCompoundsS.No.Cell LinesCompounds
11483190H295R3179KB-V(+VLB)6268R-HepG21
28898191H-3581180KB-V(-VLB)1269RKO1
3(RBL)-2H3192H-4411181KB-V116270RPMI6
4103E493H-46022182KB-V1-2271RPMI-79515
51A9894H4-II-E8183KB-V1+2272RPMI-82267
61F6295H5202184KBv2002273RPMT-82261
722Rv1496H-6611185KB-VIN24274RT43
826-L53897H-74023186KM-124275RXF 486L5
93LL1298H-9291187KM20L23276RXF 944L5
10786-0499HA59T3188L12106277RXF-3936
1195D3100HaCaT1189L5178y13278SB12
129KB2101HCC-29985190L613279SB32
13A-278029102HCC-44B23191L92920280SCABER3
14A-2982103HCC-50D31192LAC3281SCC151
15A-37510104HCE71193LM-33282SCC251
16A375-S21105HCT-11655194LNCaP93283Seg-11
17A-4271106HCT-1560195LoVo7284SF-26852
18A-43119107HCT-826196LOX-IMVI24285SF-2957
19A-49853108HEC-46R12197LP071286SF-5399
20A-540811109HEK-2936198LS174T1287SGC-790121
21A549343110HeLa97199LTEP-a-22288SH101-P43
22A549-T122111Hela-S31200LU-162289SH-J11
23ACHN21112Hela-TG1201LXFA 629L5290SH-SY5Y1
24AGS12113Hep 2,2,151202LXFL 529L5291SiHa1
25AsPC-11114Hep G2118203M-1099292SK-282
26B1636115HEp-231204M-143293SK-372
27B16 melanoma 4A525116Hep-3B16205M211294SK-BR-32
28B16(F10)24117Hepa 1c1c766206M-4-BEU3295SKCO11
29B16-BL622118Hepa59T/VGH6207Malme-3M14296SK-LU16
30B16-F03119HEPA-2B1208MAXF 401NL5297SK-Mel-1031
31B16-F14120HEPA-3B5209MB-MDA-2311298SK-Mel-1471
32BC15121Het-1a1210MCF-10A2299SK-MEL-240
33BC-146122HL-60217211MCF-7466300SK-Mel-287
34Bcap-373123HL-60/MX22212MCF-7/TH1301SK-MEL-304
35BEL-740216124HN121213MDA2311302SK-MEL-520
36BFTC-9053125HN171214MDA-MB-23137303SK-MES-11
37BGC1126HO-49801215MDA-MB-2731304SK-N-AS2
38BGC-82311127HO-89107216MDA-MB-43511305SKNSH7
39Bic-11128HONE-112217MDA-MB-435 ER-9306SK-OV-331
40BPrc13129HOP-621218MDA-MB-4533307SMMC-754111
41BT-203130HOP-925219MDA-MB-46814308SMMC-77217
42BT-4741131HOS7220MDA-N1309SN-12C2
43BT-5494132HOS-15221MDCK1310SNB-192
44BxPC-34133HPCC1222ME-1802311SNB-755
45C326134HPGBM1223ME-3086312SNB-781
46C4-21135HPOC1224Mel212313SNU-C514
47C67136HS27A1225MEL-281314SPC-A-14
48Caco-237137HS578T3226MEXF 462NL5315SR1
49CAKI3138HSC-239227MEXF 514L5316SW-11161
50CAKI-13139HSC-310228MGC-8033317SW-48021
51CaOV37140HSC-39K61229MiaPaCa-26318SW-62016
52Capan-12141HSC-40A11230MKN-289319SW-6267
53Caski2142HSC-41E62231MKN-459320SW-6802
54CCRF-CEM9143HSC-42H1232MKN-71321SW-8722
55CCRF-HSB-225144HSC-43C11233Molt-420322SW-9001
56CEM7145HSC-45M23234Molt-4F3323T246
57CEM/ADR50002146HSG26235MRC55324T-47D14
58CEM-SS7147HT12236MV32325T-47D-ER-1
59ChaGo-K-11148HT-108065237NALM-61326TAOc1BPrc13
60CL1-09149HT-11978238NCI/ADR-RES3327TE-6715
61CL1-51150HT-13763239NCI-6012328TGBC11TKB25
62CNE2151HT-1442240NCI-H18738329THP-11
63CNE32152HT-29193241NCI-H2261330TK-108
64Col-239153HTB 1401242NCI-H234331TrHBMEC1
65Colo-20519154HUH710243NCI-H322M1332TSGH1
66Colo-3203155HUVEC3244NCI-H46025333TSGH83013
67COLO320DM1156IA93245NCI-H5226334U-25117
68Colo-382157IA9-PTX103246NCI-H691335U-2661
69Colon 261158IEC61247NGP1336U-37315
70Colon 26-L551159IGROV16248OVCAR-311337U-87-MG10
71COR-L236160J774 8249OVCAR-41338U-93728
72CRL-15793161J-774-A11250OVCAR-55339UACC-2571
73CT-263162J825251OVCAR-86340UACC-6211
74DBTRG2163JB69252P-388140341UM-22b1
75DLA1164Jurkat12253PA-11342UM-SCC-11
76DLD-114165Jurkat E6.117254PACA-251343UM-SCC-17B1
77DMS-11410166JurkatCAM1.62255PANC-14344UO-3117
78DU-14544167K-56268256PC-3138345UXF 1138L5
79EAhy-9262168K562/ADM2257PC-3M1346W-2561
80Eca-1094169K562-r1258PC-65347WEHI-16413
81EKVX1170K562-s1259PCI-37a1348WI-3817
82FM3A9171KATO-III1260PF-3822349WIDR1
83FTC2381172KB298261PK-11350WS12
84G3615173KB-167262PLC/PRF/52351X-172
85GBC-SD1174KB-3-16263PMN3352XF-4982
86GTB2175KB-7d4264PTX108353ZR-75-123
87GXF 251L5176KB-C28265Raji1---
88H12992177KB-CPT3266RAW26415---
89H19751178KB-TAX502267RAW264.78---









Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.