NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Xindongnin B

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
COX-2cytochrome c oxidase subunit II4513Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----The impact of this compounds was examined on the expression of two NF-kappaB downstream gene products, including mRNA and the protein levels of COX-2 and iNOS in LPS-activated RAW264.7 cells; It suppressed LPS-induced COX-2 protein and mRNA levels in a concentration-dependent manner.15872117

 






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