NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Tectorigenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Human promyelocytic leukemiaHL-6022.3 µM---Tectorigenin decreased the Bcl-2 protein levels in the cells in a concentration-dependent manner.11642314
CASP3caspase 3, apoptosis-related cysteine peptidase836Liver CancerHUH7----Compound showed at least a 50%increase in caspase activity showing the ability of these flavonoids to induce apoptosis in HuH-7 cells21495101
EGFRepidermal growth factor receptor1956Epidermoid carcinoma A-431----Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF11642314

 






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