NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Silymarin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PARP1poly (ADP-ribose) polymerase 1142preneoplastic epidermal keratinocytesJB6 C141----Silymarin-induced apoptosis in JB6 C141 cells primarily mediated through a p53-dependent pathway, and p53-independent pathway seems to have a minor role. p53-dependent pathway involves the activation of PARP.15713892

 






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