NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Phloroglucinol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
VEGFAvascular endothelial growth factor A7422Lewis Lung Carcinoma3LLL----Phloroglucinol inhibits multiple VEGF-dependent EPC bioactivities, including the VEGF-dependent tube-forming capability and VEGF-dependent migratory capacity of EPCs in vitro. Further, this compound effectively abrogates VEGF-dependent neovessel formation in vivo, leading to delayed tumor progression and angiogenesis.22496756

 






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