NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Melphalan

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CD80CD80 molecule941PlasmacytomaMOPC-315----administration of low-dose melphalan (L-PAM, L-phenylalanine mustard) to mice bearing a large MOPC-315 plasmacytoma led to a rapid up-regulation of B7-1 (CD80), but not B7-2 (CD86), expression on the surface of MOPC-315 tumor cells10843675
CD80CD80 molecule941PlasmacytomaMOPC-315 ----In the study it was show that administration of low-dose melphalan L-PAM, L-phenylalanine mustard) to mice bearing a large MOPC-315 plasmacytoma led to a rapid up-regulation of B7-1 (CD80), but not B7-2 (CD86), expression on the surface of MOPC-315 tumor cells10843675

 






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