NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Evodiamine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Breast CarcinomaNCI/ADR-RES---0.59±0.11 µMBcl-2 was also found to be phosphorylated in cells exposed to 1 mM evodiamine.The phosphorylation site of Bcl-2 protein was further identified as Ser-70 by a specific phosphor-Bcl-2-antibody.15705600

 






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