NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Coumestrol

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

B-cell CLL/lymphoma 2

Cervix Adenocarcinoma

HeLa

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In the study, coumestrol was shown to variably but significantly suppress bcl-2 protein expression in HeLa cells.

cyclin D1

Cervix Adenocarcinoma

HeLa

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Coumestrol upregulated cyclin D protein expression in HeLa cells.

Cyclin A

Cervix Adenocarcinoma

HeLa

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-

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Coumestrol upregulated cyclin A protein expression in HeLa cells.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.