NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Chloroquine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AKT1v-akt murine thymoma viral oncogene homolog 1207TumorsCT-26----The results showed that 25-100 µmol/L chloroquine clearly reduced the phosphorylated levels of Akt indicating that chloroquine can inhibit Akt activities19194831
MAPK3mitogen-activated protein kinase 35595TumorsCT-26----The results showed that 25-100 µmol/L chloroquine clearly reduced the phosphorylated levels of p44/42 MAPK, indicating that chloroquine can inhibit p44/42 MAPK activities19194831

 






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