NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Andrographolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BIDBH3 interacting domain death agonist637HepatomaHep G2----When cells were pretreated with pan-caspase inhibitor (z-VAD-FMK) or caspase 8 inhibitor (z-IETD-FMK), the decrease of full length of Bid caused by Andro was prevented,suggesting that Bid cleavage is mediated by caspase 8 activation.16740251

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.