NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Andrographolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BAXBCL2-associated X protein581HepatomaHep G2----Bax conformational changes were proven to be caspase 8-dependent, as pretreatment with caspase 8 inhibitor (z-IETD-FMK) almost completely abolished the Andro-induced conformational changes of Bax16740251

 






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