NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 11-hydroxytephrosin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.74.21±1.67 µg/mL---Compounds inhibited NF-kappaB activity in TNF-alpha-stimulated HeLa cell-based reporter gene assays.18841906
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Cervix AdenocarcinomaHeLa0.19±0.06 µg/mL---Compounds inhibited NF-kappaB activity with IC50 values of 0.19 in TNF-alpha-stimulated HeLa cell-based reporter gene assays.18841906

 






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