NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: (R)-tylophorine

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cyclin-A2-2

Hepatoma

Hep G2

-

-

-

237±32 nM

In asynchronized HepG2 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.

cyclin-A2-2

Nasopharyngeal carcinoma cells

HONE-1

-

-

-

114±6 nM

In asynchronized HONE-1 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.

cyclin-A2-2

Carcinoma

NUGC-3

-

-

-

134±9 nM

In asynchronized NUGC-3 , cyclin A2 level was significantly lower with tylophorine treatment than with DMSO and dehydro-tylophorine treatment.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.