NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Tetrandrine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AKT1v-akt murine thymoma viral oncogene homolog 1207Colon CancerHT-29----AKT inhibition and GSK3-Beta activation are involved in tetrandrine mediated changes of cell cycle or apoptosis regulatory proteins in HT-29 cells.18437054
AKT1v-akt murine thymoma viral oncogene homolog 1207Lung adenocarcinomaA549----Results suggest that Tetrandrine selectively inhibits the proliferation of lung cancer cells by blocking Akt activation.19255520

 






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