NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Squamocin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 59252Colon cancerSW-620----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of Aurora B in cancer cells and decreased the protein expression levels of aurora .21299907
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 59252Human Glioblastoma MultiformeGBM8401----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of Aurora B in cancer cells and decreased the protein expression levels of aurora .21299907
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 59252Liver CancerHUH7----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of Aurora B in cancer cells and decreased the protein expression levels of aurora .21299907

 






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