NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Sanguinarine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
birc5abaculoviral IAP repeat-containing 5a373110Prostate CancerDU145----The tumor growth in sanguinarine-treated group was suppressed starting at 31 days post cell inoculation and throughout the treatment period until 56 days when the mice were sacrificed . The levels of survivin protein expression in tumors were decreased in sanguinarine treatment group compared to the control group. These data demonstrated that sanguinarine was able to suppress the tumor growth of DU145 human prostate cancer cells.21318089

 






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