Compound: S-allylmercaptocysteine

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

BAX

BCL2-associated X protein

Gastric Carcinoma

SNU-1

Levels of Bax mRNA and protein were significantly increased by SAMC treatment in a concentration-dependent manner.

caspase 3, apoptosis-related cysteine peptidase

Gastric Carcinoma

SNU-1

Caspase-3 activities were increased 2.1-, 2.6-, and 3.1-fold by treatment with SAM.

caspase 9, apoptosis-related cysteine peptidase

Gastric Carcinoma

SNU-1

The anti-proliferative and apoptotic effect of SAMC was associated with the induction caspase-.

tumor protein p53

Gastric Carcinoma

SNU-1

Levels of both the protein and mRNA of p53 were significantly increased by treatment with S-allylmercaptocysteine.

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase