NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: psorothamnones B

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PRKCAprotein kinase C, alpha5578Breast adenocarcinomaMCF-7----Compound demonstrated moderate inhibitory activity against protein kinase C. These heterocyclic natural products may serve as lead compounds for synthesis of more potent PKC inhibitors.11000028
PRKCAprotein kinase C, alpha5578Colon CancerHT-29----Compound demonstrated moderate inhibitory activity against protein kinase C. These heterocyclic natural products may serve as lead compounds for synthesis of more potent PKC inhibitors.11000028
PRKCAprotein kinase C, alpha5578Lung adenocarcinomaA549----Compound demonstrated moderate inhibitory activity against protein kinase C. These heterocyclic natural products may serve as lead compounds for synthesis of more potent PKC inhibitors.11000028
PRKCAprotein kinase C, alpha5578MelanomaMalme-3M----Compound demonstrated moderate inhibitory activity against protein kinase C. These heterocyclic natural products may serve as lead compounds for synthesis of more potent PKC inhibitors.11000028
PRKCAprotein kinase C, alpha5578MelanomaSK-MEL-5----Compound demonstrated moderate inhibitory activity against protein kinase C. These heterocyclic natural products may serve as lead compounds for synthesis of more potent PKC inhibitors.11000028

 






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