NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Pinocembrin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PARP1poly (ADP-ribose) polymerase 1142Colon cancerHCT-116----PARP is an important enzyme responsible for the DNA repair and is a preferred substrate for processed caspase-7 and -3.Western blot analysis of treated samples shows that cleavage of PARP is evident only around 48 h of drug exposure.17186548

 






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