NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Naringenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 11588Breast adenocarcinomaMCF-72 µM---Naringenin inhibited aromatase activity with IC50 value of about 2µM.22209285
CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 11588Adrenocortical CarcinomaH295R85 µM---The first inhibitory effects on aromatase activity in vitro in H295R cells were observed at concentrations above 10 mM for naringenin and above 1 mM for chrysin and apigenin.15319488

 






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