NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Morusin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Colon CancerHT-29----Increase in the active form of Caspase-3 was also observed at 12-72 h. PARP is a substrate of caspase-3 and Active caspase-3 can also catalyze DFF-45 and DFF-35. Cleavage of PARP and translocation of DFF-40 in nuclei indicate the activity of caspase-3 and also suggest the results of DNA fragmentation.18485277

 






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