NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Morin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
COX-2cytochrome c oxidase subunit II4513Hepatocellular Carcinoma-----During this cancer, inflammation of the liver cause due to up-regulation of NF-kappaB-p65 and COX-2.Oral supplementation of morin (500 ppm in diet) to DEN-induced hepatocellular carcinoma down-regulated the expression of COX-2, thereby preventing inflammation and angiogenesis mediated hepatocellular carcinogenesis.19539802

 






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