NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: mahanine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PARP1poly (ADP-ribose) polymerase 1142Human promyelocytic leukemiaHL-60----Cleavage of PARP in HL-60 cells started at 4 hr after treatment with mahanine (10 mM) and became clearer when caspase-3 activation increased significantly.14667927

 






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