NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: mahanine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP6caspase 6, apoptosis-related cysteine peptidase 839Human promyelocytic leukemiaHL-60----mahanine treatment resulted in time dependent increase in the proteolytic activity of various caspases in HL-60 cells by comparing the activity of each caspases in the control cells. A significant increase in the activity of caspase-6 was observed since 8 hr of mahanine treatment.14667927

 






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