NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: L-epicatechin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MAPK1mitogen-activated protein kinase 15594HepatomaHep G2----Epicatechin incubation resulted in a time-dependent activation of ERKs, evoking an increase of ERK phosphorylation as early as after 5 min of incubation.18495458
PRKCAprotein kinase C, alpha5578HepatomaHep G2----Treatment of HepG2 cells with epicatechin enhanced PKC-alpha levels after 30 min, and protein levels continued to increase up to 18 h.18495458

 






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