NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Isoliquiritigenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
VEGFAvascular endothelial growth factor A7422Prostate CancerDU-145----Results of VEGF ELISA and Western blot analysis showed that ISL inhibited basal and EGF-induced secretion of VEGF by DU145 cells. VEGF plays a major role in tumor angiogenesis, so inhibiting VEGF production is a promising strategy for the treatment of cancer. Here they demonstrate that ISL inhibits VEGF production in DU145 cells.18824345

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.