NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Genistein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDK1cyclin-dependent kinase 1983Bladder CancerJ82----A dose-dependent inhibition of the cdc2 kinase activity, corresponding to the observed cell cycle arrest effect, was observed in most bladder cancer cell line10656454
CDK1cyclin-dependent kinase 1983Bladder CancerT24----A dose-dependent inhibition of the cdc2 kinase activity, corresponding to the observed cell cycle arrest effect, was observed in most bladder cancer cell line10656454
CDK1cyclin-dependent kinase 1983UroepithelialsHT-1376----A dose-dependent inhibition of the cdc2 kinase activity, corresponding to the observed cell cycle arrest effect, was observed in most bladder cancer cell line10656454
CDK1cyclin-dependent kinase 1983Human MelanomaOCM-1----Genistein inhibited CDK-1 by 50-70.11322924

 






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