NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Eupafolin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Cervix AdenocarcinomaHeLa----Bcl-2 family proteins are known to control apoptosis that occurs via the mitochondrial pathway by maintaining a balance between pro- and anti-apoptotic members. The levels of Bcl-2 were reduced after eupafolin treatment. These findings suggest that eupafolin modulates the protein levels of Bid and Bcl-2, and this results in the release of cytochrome c from mitochondria.20397191

 






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