NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Erythrabyssin II

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PTPN1protein tyrosine phosphatase, non-receptor type 15770Breast adenocarcinomaMCF-7>30 µM---PTP1B is overexpressed in human breast cancer, and inhibition of PTP1B delays erbB2-induced mammary tumorigenesis and protects from lung metastasis.Among the isolated compounds, erythrabyssin II along with isolated compounds was evaluated for their inhibitory effects on protein tyrosine phosphatase-1B (PTP1B), as well as their growth inhibition on MCF7.19836230

 






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