NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Epigallocatechin gallate

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Colon CancerHT-29----After the treatments of different doses of Epigallocatechin gallate (EGCG) , the induction of caspase-3 activity in HT-29 cells was consistent with the results shown in DAPI staining and DNA fragmentation experiments. 100 mM of EGCG led to ~8-fold induction of caspase-3 activity after 24 h treatment.12819184

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.