NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Curcumin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MMP14matrix metallopeptidase 14 (membrane-inserted)4323Murine melanoma B16(F10)----On treatment of B16F10 cells with curcumin (15 mM for 15 days), MT1-MMP expression was reduced virtually to background levels when compared with control B16F10 cells. MT1-MMP expression remained at background levels even after 28 days of drug withdrawa.15219947

 






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