NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: cryptolepine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PARP1poly (ADP-ribose) polymerase 1142Human promyelocytic leukemiaHL-60----A treatment for 24 h with 5 mM cryptolepine suffices to induce 50% cleavage of poly ADP-ribose. polymerase in the leukemia cells and a quantitative cleavage was observed using 10 mM cryptolepine.11099695

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.