NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Chrysin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NOS2nitric oxide synthase 2, inducible4843Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----Chrysin compounds do not have any nitrogen, but chrysin definitely inhibited iNOS enzyme catalysis as monitored by the hemoglobin oxidation assay.14597150
NOS2nitric oxide synthase 2, inducible4843Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----NO induction by LPS treatment in cultured Raw264.7 cells was prevented up to 80% by chrysin (at 50 M).14597150

 






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