NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Celastrol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790T cell leukemiaJurkat T----Jurkat cells stimulated with TNF-a or PMA strongly induced DNA-binding activity of NF-kB. However, pretreatment of celastrol dose-dependently inhibited DNA-binding activity of NF-k B induced by TNF-a or PM.16984800

 






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