NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Carnosol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----Carnosol inhibited LPS-induced NF-kappaB transcriptional activity.12082020
NOS2nitric oxide synthase 2, inducible4843Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----Data suggested that carnosol modulate iNOS expression at the transcriptional level.12082020

 






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