NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Brucine N-oxide

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

prostaglandin E receptor 3 (subtype EP3)

Hepatocellular carcinoma

SMMC-7721

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brucine dose-dependently decreased the protein abundance of COX-2.Meanwhile, brucine also dose-dependently suppressed the release of PGE2 content in the supernatant of SMMC cell.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.