NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Beta-Lapachone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCNB1cyclin B1891Colon cancerSW-620----Cyclin B1 expression was prominently up-regulated, a finding consistent with the late S-and G2/M-phase arrest induced by ,B-lapachone at 24 hr post-treatment.10656873
CCNB1cyclin B1891Colon AdenocarcinomaDLD-1----Cyclin B1 was prominently down-regulated, which is consistent with the early S-phase arrest induced by beta-lapachone at 24 hr post-treatment.10656873
CCNB1cyclin B1891Colon CancerSW-480----In SW480 cells,the expression of the G2 /M phase-specific cyclin B1 was prominently down-regulated10656873

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.