NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Baicalein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCND1cyclin D1595Lung squamous CarcinomaCH27----The level of cyclin D1 protein was decreased during 50µM baicalein treatment for 24 h .Their data indicated that G0/G1-phase-regulating proteins cyclin D1 and cdk 4 expressed at low levels in baicalein-induced apoptosis. The modifications of these cell cycle-associated proteins induced by baicalein appear to perturb the cell progression through the S-phase.15868934

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.