NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Baicalein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCNB1cyclin B1891Lung CancerH-460----Levels of Cyclin B1 protein was decreased during 50 µM baicalein treatment 24 .17050058
CCNB1cyclin B1891Lung squamous CarcinomaCH27----The level of cyclin B1 protein was decreased during 50 µM baicalein treatment for 24 h. Their data indicated that G2/M-phase-regulating cyclin B1 are expressed at low levels in baicalein-induced apoptosis. The modifications of these cell cycle-associated proteins induced by baicalein appear to perturb the cell progression through the S-phase.15868934

 






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