NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Apigenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
VEGFAvascular endothelial growth factor A7422Lung adenocarcinomaA549----Apigenin inhibited VEGF transcriptional activation through the hypoxia-inducible factor 1 (HIF-1) binding site and specifically decreased HIF-1alpha but not HIF-1Beta subunit expression in the cells.15947208

 






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