NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Alpha-mangostin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDK7cyclin-dependent kinase 71022Breast CarcinomaMDA-MB-231----Real-time analysis revealed that the expression of p21cip1 was up-regulated and CHEK2 expression tended to increase for more than 6 h after alpha-mangostin treatment. p21cip1 is a cyclin dependent kinase inhibitor and the encoded protein binds to and inhibits the activity of cyclin-CDK2 (CDK: cyclindependent kinase.22577295

 






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