NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 6,8-Diprenyleriodictyol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836LeukemiaCCRF-CEM11.6 µM---6,8-Diprenyleriodictyol strongly induced apoptosis and also cell cycle arrest in the G2/M phase. This high apoptosis induction is confirmed by the high caspase 3activity in CCRF-CEM cells up to 10.82-fold increased activity (as compare to non treated cells) being observed after treatment with 23.1 µM.21800276

 






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