NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Polyphyllin I

ModelsTargetInhibitory ConcRemarkReference
BALB/c nude mice (5 weeks old) were subcutaneously inoculated with A549 cells--The results suggested that the Polyphyllin I (PPI) could significantly inhibit the tumor growth of A549 cells in the nude mice. The tumor growth rate in the PPI group was much lower than that in any other group (P<0.05). On the 30th day of inoculation, the tumor size and weight in the PPI group were 18.23±5.36 mm3 and 0.03±0.009 g, respectively, which was markedly lower than the other controlled groups.20978038

 






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