Compound	9-Aminocamptothecin
NPACT-Id	NPACT01108
IUPAC	-
Synonyms	Camptothecin, 9-amino-;9-AC;9-Amino-20-(S)-camptothecin;9-Amino-20-camptothecin;(4s)-10-amino-4-ethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;(S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano(3;,4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;1H-Pyrano(3;,4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 10-amino-4-ethyl-4-hydroxy-, (S)-;
PubChem Id	72402
Class	Alkaloids
In-vitro anticancer activity	4 cancer cell lines
In-Vivo anticancer activity	No
Targets	TOP1MT \| All \|
Properties	Physical Elemental Topological
InChi Key	FUXVKZWTXQUGMW-FQEVSTJZSA-N
InChi	1S/C20H17N3O4/c1-2-20(26)13-7-16-17-10(6-11-14(21)4-3-5-15(11)22-17)8-23(16)18(24)12(13)9-27-19(20)25/h3-7,26H,2,8-9,21H2,1H3/t20-/m0/s1
SMILES	O1Cc2c([C@@](O)(CC)C1=O)cc1n(Cc3c1nc1c(c3)c(N)ccc1)c2=O
SMART	[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C([H])C3=C(N([H])[H])C([H])=C([H])C([H])=C3N=C12)C([H])([H])C([H])([H])[H]
CAS No.	91421-43-1
Structure Download
Cross Refrence in other databases
	Super Natural	-
	CTD	C080125
	HIT	-
	NCI-60 GI₅₀ data	91421-43-1
Suppliers	AAA Chemistry, ABI Chem, Ambinter, IS Chemical Technology, Kingston Chemistry, TCI (Tokyo Chemical Industry), Tractus,
Drug-Likeliness Filters	Lipinski's rule of five	Yes
	Ghose filter	No
	Veber filter	Yes
	Muegge Filter	Yes
Similarity Search	Human metabolite database	FDA approved drugs

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase