Compound	Matrine
NPACT-Id	NPACT00760
IUPAC	-
Synonyms	(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
PubChem Id	91466
Class	Alkaloids
In-vitro anticancer activity	2 cancer cell lines
In-Vivo anticancer activity	Yes
Targets	BAX \| BCL2 \| CASP3 \| CASP8 \| CASP9 \| Fas \| PCNA \| All \|
Properties	Physical Elemental Topological
InChi Key	ZSBXGIUJOOQZMP-JLNYLFASSA-N
InChi	1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1
SMILES	O=C1N2[C@@H]([C@@H]3[C@H]4N(CCC3)CCC[C@H]4C2)CCC1
SMART	[H]C1([H])[N@]2C([H])([H])C([H])([H])C([H])([H])[C@]3([H])[C@]4([H])N(C(=O)C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])[C@]23[H]
CAS No.	519-02-8
Structure Download
Cross Refrence in other databases
	Super Natural	000519028
	CTD	C034244
	HIT	C0333
	NCI-60 GI₅₀ data	-
Suppliers	ABI Chem, AKos Consulting & Solutions, Ambinter, ChemMol, Selleck Chemicals, TCI (Tokyo Chemical Industry),
Drug-Likeliness Filters	Lipinski's rule of five	Yes
	Ghose filter	Yes
	Veber filter	Yes
	Muegge Filter	Yes
Similarity Search	Human metabolite database	FDA approved drugs

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase