Vaccine Candidates


These table show the number of virulent/secretion/genetic variance proteins among various strain of Mycobacterium species. This protein were searched using global alignments and filtered using sequence identity of cut 95%. The each protein is then linked NCBI. We believe these are proteins are the vaccine candidates among diverse range of mycobacterial subtypes. Here, user can find the corresponding proteins in other strains of tuberculosis. It could be important for the user that a particular protein is conserved in drug-resistant or drug-susceptible strain of tuberculosis and based on that user can decide candidate antigen of their choice.


Table1: Virulent proteins

idM africanum GM041182M canettii CIPT 140010059 3861M canettii CIPT 140010059M canettii CIPT 140060008M canettii CIPT 140070008M canettii CIPT 140070010M canettii CIPT 140070017Mtb 7199-99Mtb CCDC5079Mtb CDC 1551Mtb CTRI-2Mtb F11Mtb KZN 4207-3996Mtb KZN 4207Mtb UT205Mtb CCDC5180Mtb KZN 1435Mtb KZN V2475Mtb KZN 605Mtb KZN R506Mtb RGTB327Mtb RGTB423Mtb H37Rv broadMtb H37RvMtb H37RaM bovis AF2122 97M bovis BCG str KoreaM bovis BCG str MexicoM bovis BCG str Pasteur 1173P2M bovis BCG str Tokyo 172M abscessus ATCC 19977M avium 104M avium K-10M chubuense NBB4M gilvum PYR-GCKM gilvum Spyr1M indicus prani MTCC 9506M intracellulare ATCC 13950M intracellulare MOTT-02M intracellulare MOTT-64M kansasii ATCC 12478M leprae Br4923M leprae TNM liflandiii 128FXTM marinumM massiliense GO 06M rhodesiae NBB3M smegmatis JS623M smegmatis MC2 155M smegmatis MKD8M smegmatis str MC2 155M smegmatis str MC2 155 secondM ulcerans Agy99M vanbaalenii PYR-1Mycobacterium sp JDM601Mycobacterium sp JLSMycobacterium sp KMSMycobacterium sp MCSMycobacterium sp MOTT36Y
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Rv0166 O07411339630247340625203433633183433625267433640297433629257433633183440579615385993277038599693814882135837529437029763264439238488638598968425379708831365694539243058129772961900395136856156073071486599303179134444906216037876991112163607822498855100000000000000000000000000000
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Rv0199 O536503396302783406252364336332174336253014336403314336292894336332174405796493859933090385996971148821392375294403297632679392384920385989716253797121313656979392430614297729653383306132386003283395136891156073401486599633179137744906219537876994412163611122498858400000000000000000000000000000
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Rv0348 O062993396304193406253790433625444000440579800385993449158397343859971221488215443752945562976328333923850663859898552537972743136571373924307662977298083833062730395137044156074891486601143179152644906234337877009512163626222498873400000000000000000000000000000
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Rv0491 Q111563396305613406255174336335044336255844336406124336295764336335044405799473859935851583988238599726314882169037529470129763297739238520938598998725379742031365728139243090929772995238330640638600353139513719115607632148660258317916714490624933787702411216364072249888790118466224414100813924144960040603283937880160737975656437976409324017351300443489244183980840000000011861965300000387877949
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Rv0820 O538323396308863406258354336338714336259044336409384336299034336338714405802853859938821584023338599759914882202637529504129763333239238553438599028325379776731365764139243124829773031603860038393951375401560796014866059831792008000000000000000000000000000000000
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Rv0899 P655933396309643406259104336339534336259824336410194336299884336339534405803640158403183859976801488221093752973102976334183923856090253800076313657730392433516297730403383306791386003911395137622156080391486606773179208744906293537877065612163682222498929300000000000000000000000000000
Rv0930 O86345339630993340625939433633983433626014433641054433630032433633983440580395385993984158403533859977111488221393752972802976334523923856403859903842538000433136577653924334832977304373833068190395137656571167991486607093179211744906297037877068712163685322498932400000000000000000000000000000
Rv0931c O05871339630994340625940433633984433626015433641055433630033433633984440580396385993985158403543859977121488221403752972792976334533923856413859903852538000423136577663924334822977304383833068200395137657156080711486607100000000000000000000000000000000000
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Rv1348 P6339133963141734062636443363441243362645043364150043363046443363441244058082638599437315840803385998133148822569375296845297633901392386039385990773253799604313658222392433056297730889383307217386004334395138096156084881486611373179254444906342237877111312163727922498975300000000000000000000000000000
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Rv1964 O539650340626973433634999433627059433642098433631073433634999440581437385994935158414393859987400375296238297634533392386617385991319253798988313658854392432451297731521383307780386004916395138740156091011486617730000000000000000000000000000000000
Rv1979c Q10875339632017340626992433635020433627080433642121433631094433635020440581452385994953158414553859987551488231933752962232976345483923866323859913372537989733136588693924324372977315360386004929395138755156091161486617883179315800022499035600000000000000000000000000000
Rv2027c O534733396320673406270384336350824336271324336421814336311434336350824405815040158415143859988071488232433752961682976346043923866780253798916313658925392432380297731592383307840386004978395138809156091641486618413179320944906408137877175812163791322499040700000000000000000000000000000
Rv2031c P0A5B733963207134062704243363508643362713643364218543363114743363508644058150838599500415841518385998811148823247029763460839238668238599138903136589293924323762977315960386004981395138813156091681486618453179321444906408537877176212163791722499041100000000000000000000000000000
Rv2032 O5347633963207234062704343363508743362713743364218643363114843363508744058150938599500515841519385998812148823248375296163297634609392386683385991390253798911313658930392432375297731597383307845386004982395138814156091691486618463179321544906408637877176312163791822499041200000000000000000000000000000
Rv2069 P668093396321093406270804336351284336271754336422294336311914336351284405815453859950380385998849002976346463923867193859914230313658968392432339297731633383307876386005012395138852156092061486618833179325244906412437877180012163795422499044800000000000000000000000000000
Rv2097c P6494333963213234062711043363516743362721543364227743363121943363516744058157338599506415841588385998878148823311375296098297634678392386748385991450253798844313659001392432310297731666383307905039513888215609234148661912317932804490641543787718281216379822249904761696292691184649984140793100000379754421024017341722123016615827689443490874183983082000000011861783900000387875711
Rv2115c P63345339632148340627124433635183433627231433642294433631232433635183440581590385995081158416073859988921488233263752960792976347003923867623859914642537988233136590233924322892977316880386005056395138901156092521486619303179329544906417037877184412163799722499049100000000000000000000000000000
Rv2136c O06239339632168340627145433635204433627252433642316433631254433635204440581611385995099158416273859989131488233453752960582976347233923867823859914822537988013136590473924322682977317123833079440395138923156092731486619513179331644906419237877186612163801822499051200000000000000000000000000000
Rv2200c P638543396322283406272054336352670433642386433631317433635267440581675015841691385998975148823407375295993297634789392386843025379873531365911439243220329773178000395138990156093371486620173179337944906425737877193012163808122499057500000000000000000000000000000
Rv2224c P65823339632252340627229433635292043364241143363134343363529244058170038599518615841716385999000148823432375295968297634814392386867385991567253798710313659139392432179297731805383308021386005154395139015156093611486620423179340444906428237877195512163810622499060000000000000000000000000000000
Rv2234 P6571633963226034062723843363530304336424234336313544336353034405817110158417263859990091488234423752959572976348283923868760253798699313659153392432168297731819383308034386005165395139026156093711486620543179341444906429337877196612163811622499061000000000000000000000000000000
Rv2246 P63456339632272340627250433635316043364243643363136743363531644058172338599520816135006838599902114882345437529594529763484139238688838599158925379868631365916639243215529773183200395139039156093831486620673179342644906430637877197812163812822499062200000000000000000000000000000
Rv2349c P952453396323743406273604336354290433642549433631465433635429440581827385995297158418563859991291488235503752958392976349473923869953859916772537985773136592733924320472977319383833081400395139153156094861486621770000000000000000000000000000000000
Rv2350c P952463396323753406273614336354300433642550433631466433635430440581828385995298158418573859991301488235513752958382976349483923869963859916782537985763136592743924320462977319390386005268395139154156094871486621780000000000000000000000000000000000
Rv2351c Q04001339632376340627362433635431043364255143363146743363543144058182901584185801488235523752958372976349493923869973859916792537985753136592753924320452977319400386005269395139155156094881486621790000000000000000000000000000000000
Rv2383c P7171733963240934062739443363546404336425774336314984336354644405818593859953281584189538599916314882358537529580329763498439238702438599170825379854031365931139243201029773197700395139187156095201486622153179356044906444437877211312163826222499075600000000000000000000000000000
Rv2428 Q7BHK8339632455340627441433635511043364262743363154643363551144058190538599537015841949385999209148823631375295755297635036392387068385991749253798492313659363392431962297732028383308213386005342395139234156095651486622633179360844906449737877216212163831022499080400000000000000000000000000000
Rv2445c P84284339632473340627459433635527043364264443363156243363552744058192338599538315841969385999227148823647375295738297635053392387086385991762253798475313659380392431945297732044383308227386005356395139252156095821486622803179362644906451637877218012163832822499082200000000000000000000000000000
Rv2452c O531793396324803406274664336355330433642650043363553344058193001584197638599923400039238709300000003951392591560958914866228731793633037877218712163833522499082900000000000000000000000000000
Rv2703 P0A6023396327153406277044336357650433642889433631804433635765440582180385995609158422413859994831488238933752954822976353113923873353859919882537982153136596403924316902977323073833084670395139517156098401486625443179387544906477037877243312163857822499107000000000000000000000000000000
Rv2711 P0A67233963272334062771243363577304336428974336318124336357734405821883859956141584224938599949114882390037529547529763531939238734338599199325379820731365964839243168329773231538330847538600558639513952515609848148662552317938834490647783787724411216385862249910780000000000240169687000000000000000000
Rv2745c O33287339632757340627746433635804043364293143363184343363580444058222301584228538599952614882393337529544129763535439238737702537981733136596843924316492977323513833085073860056183951395601560988214866258731793919037877247812163862322499111500000000000000000000000000000
Rv2869c O33351339632878340627862433635934043364306043363196543363593444058234738599575515842411385999654148824060375295310297635485392387495385992132253798042313659817392431518297732484383308620386005734395139692156100061486627123179404644906494637877260612163875122499124300000000000000000000000000000
Rv2930 Q1097633963293734062792143363599604336431224336320254336359964405824090158424763859997150375295251297635549392387557003136598803924314592977325483833086730395139754571170381486627763179410744906501037877266812163881222499130400000000000000000000000000000
Rv2938 P962073396329453406279294336360040433643130433632033433636004440582417015842484385999723148824127375295243297635557392387565385992196253797974313659888392431451297732556383308681386005801395139762156100751486627843179411544906501837877267612163882022499131200000000000000000000000000000
Rv2941 P962903396329483406279324336360070433643133433632036433636007440582420385995826158424873859997261488241303752952402976355603923875683859921992537979713136598913924314482977325593833086840395139765156100781486627873179411844906502137877267912163882322499131500000000000000000000000000000
Rv2945c P6530633963295334062793443363600904336431354336320394336360094405824250158424933859997311488241343752952362976355653923875733859922032537979663136598963924314442977325643833086880395139768156100821486627923179412244906502737877268312163882722499131900000000000000000000000000000
Rv2946c P962850340627935000004405824260158424943859997321488241353752952352976355663923875743859922042537979653136598973924314432977325650386005807395139769156100831486627930000000000000000000000000000000000
Rv2947c P962840340627936000004405824270158424953859997331488241360039238757538599220500003833086910395139770156100841486627940000000000000000000000000000000000
Rv3018 P3150033963302534062800843363608400043363608444058250038599589800148824208375295159297635646038599227125379788731365997639243136629773264400395139846571170451486628693179419544906510437877275712163890022499139200000000000000000000000000000
Rv3082c Q0686133963309034062807304336282234336432750044058256138599596315842652385999871148824274375295092297635716392387708385992337253797818313660047392431299297732715383308824386005930395139913156102191486629363179426144906517337877282512163896722499145900000000000000000000000000000
Rv3083 O533003396330913406280744336361530433643276433632171433636153440582562385995964158426533859998721488242753752950912976357173923877093859923382537978173136600483924312982977327160386005931395139914156102201486629373179426244906517437877282612163896822499146000000000000000000000000000000
Rv3133c P95193339633140340628109433636212433628261433643315433632232433636212440582616385996013158427063859999191488243273752973992976357753923877543859923832538001663136601053924336072977327720386005979395139965156102691486629873179430944906522637877287412163901622499150800000000000000000000000000000
Rv3151 P9517533963315834062812743363623104336433344336322514336362314405826343859960311584272738599993714882434537529741729763579439238777238599240125380018531366012439243362629773279100395139984156102871486630063179432744906524537877289212163903422499152600000000000000000000000000000
Rv3223c P6680733963323234062820243363631743362835743364341543363232243363631744058270800386000010000392387845000029773287138330896503951400671561035914866308531794402037877306312163920322499160300000000000000000000000000000
Rv3236c Q7D5V533963324634062821543363633104336434294336323354336363314405827233859961111584282538600002514882443837529750829763588939238786038599248225380027831366021839243371829773288600395140082571170791486630993179441644906534037877298412163912522499161800000000000000000000000000000
Rv3270 P0A5023396332803406282484336363670433643463433632369433636367440582757385996143158428603860000591488244723752975422976359243923878943859925142538003133136602533924337532977329213833090050395140117156104061486631333179445044906537537877301812163915922499165200000000000000000000000000000
Rv3286c Q7D5S23396332953406282684336363870433643482433632388433636387440582773385996158158428773860000751488244883752975582976359400385992529253800329313660269392433769297732937383309020386006123395140133156104221486631493179446644906539137877303412163917522499166800000000000000000000000000000
Rv3404c P65073339633409340628382433636491043364359443363250043363649144058289638599627515842999386000197148824612375297678297636066392388011385992637253800451313660397392433889297733066383309136386006240395140260156105401486632683179458544906551737877319012163932922499182600000000000000000000000000000
Rv3409c Q573070340628387433636496433628547433643599433632505433636496440582901385996279158430043860002021488246163752976832976360713923880163859926412538004563136604023924338942977330713833091410395140265156105451486632733179459044906552237877319512163933422499183000000000000000000000000000000
Rv3414c P6681133963341934062839243363650004336436044336325104336365004405829063859962840386000207148824621375297688297636076392388021025380046131366040739243389929773307600395140270156105501486632783179459544906552737877320012163933922499183500000000000000000000000000000
Rv3416 Q50710339633421340628394433636502043364360643363251243363650244058290838599628615843012386000209148824623375297690297636078392388023385992648253800463313660409392433901297733078383309148386006251395140272156105521486632803179459744906552937877320212163934122499183700000000000000000000000000000
Rv3501c O535460000043363259644058300738599636203860002881488247083752977690392388100385992726253800543313660488392433981297733157038600632401561063714866336531794677449065611378773281121639420224991916000000406028905378797653379752577379760017240170056000000000000000000
Rv3540c P71861034062850443363663343362868104336326344336366334405830473859964051584315238600032514882474637529780729763621239238813238599276725380058131366053639243401929773320638330927238600636439514039915610676148663403317947164490656533787733201216394592249919560000000000240172830000000000000000000
Rv3542c P718590340628506433636635433628683043363263643363663544058304938599640715843154386000327148824748375297809297636214392388134385992769253800583313660538392434021297733208383309274386006366395140401156106781486634053179471844906565537877332212163946122499195800000000000000000000000000000
Rv3544c P7185703406285080433628685043363263804405830513859964091584315638600032914882475037529781129763621639238813638599277125380058531366054039243402329773321000395140403156106801486634073179472044906565737877332412163946322499196000000000000000000000000000000
Rv3545c P63709339633543000433643736044058305238599641015843157386000330148824751375297812039238813738599277225380058631366054139243402429773321103860063670156106811486634083179472144906565837877332512163946422499196100000000000000000000000000000
Rv3568c P9685033963356734062853443363667743362871100433636677440583076385996433158431813860003541488247743752978352976362423923881613859927952538006093136605663924340472977332363833092983860063910156107041486634323179474544906568137877334912163948822499198500000000000000000000000000000
Rv3614 O062693396336130043362875343364380243363270644058312238599647515843224386000400148824818375297877297636286392388205385992838253800652313660611392434089297733280383309341386006430395140473156107501486634773179479044906572737877339412163953322499203000000000000000000000000000000
Rv3615c P65087034062858043363671900043363671944058312338599647615843225386000401148824819375297878039238820638599283925380065331366061239243409029773328138330934200156107511486634783179479144906572837877339512163953422499203100000000000000000000000000000
Rv3654c O696220340628626433636759433628793004336367594405831620038600044200039238824500000000156107900317948240012163956722499206400000000000000000000000000000
Rv3666c O696343396336573406286384336367714336288050043363677144058317438599652015843280386000454148824869375297931297636342392388257385992880253800707313660667392434144297733335000156108021486635283179483644906577737877344112163957922499207600000000000000000000000000000
Rv3671c O6963900043362881143364385843363276444058317938599652515843288386000459148824875375297938039238826238599288525380071431366067239243415129773334100395140529156108071486635343179484144906578337877344712163958422499208000000000000000000000000000000
Rv3682 Q7D5290004336288234336438704336327764405831913859965371584330038600047114882488637529794903923882733859928972538007263136606843924341632977333533833094040395140541571171451486635453179485344906579537877345912163959622499209200000000000000000000000000000
Rv3763 P0A5J03396337573406287344336368654336289070433632856433636865440583275385996616158433833860005541488249683752980322976364443923883563859929762538008103136607693924342462977334383833094803860065640156108991486636293179493344906587737877354012163967722499217300000000000000000000000000000
Rv3804c P0A4V23396337990043362894700440583318385996657158434263860005961488250113752980742976364863923883983859930152538008523136608113924342882977334800386006602395140671156109401486636723179497844906592137877358412163972122499221600000000000000000000000000000
Rv3810 P0A5P433963380500433628953004336369104405833243859966631584343238600060214882501737529808029763649239238840438599302125380085831366081739243429429773348600395140677156109461486636783179498444906592737877359012163972722499222200000000000000000000000000000
Rv3823c O07800034062879243363692304336440144336329184336369234405833373859966761584344738600061514882503037529809329763650639238841738599303525380087131366083239243430729773350103860066200156109591486636913179499744906594237877360412163974122499223600000000000000000000000000000
Rv3849 P962283396338430004336440420440583363385996702158434803860006411488250583752981220392388443385993060253800900313660861392434336297733530038600664601561098514866371731795023037877363012163976722499226200000000000000000000000000000
Rv3865 P96212004336369654336290110433632956433636965440583379385996716158434973860006571488250733752981372976365503923884583859930732538009153136608763924343512977335453833095760395140735156110011486637323179503944906599037877364312163978322499227800000000000000000000000000000
Rv3867 O697320043363696743362901304336329584336369674405833813859967180386000659148825075375298139297636552392388460385993075253800917313660878392434353297733547383309578386006662395140737156110031486637343179504144906599237877364512163978522499228000000000000000000000000000000
Rv3868 O6973333963386134062884000433644060044058338238599671915843498386000660148825076375298140039238846138599307625380091831366087939243435429773354838330957900156110041486637353179504244906599337877364612163978622499228100000000000000000000000000000
Rv3874 P0A56633963386734062884600433644066043363697444058338838599672615843505386000666148825082375298146039238846738599308125380092431366088539243436029773355438330958438600666701561101014866374131795048000000000000002401683530044349345918398542000000000000000
Rv3875 P0A56400433636975433629021043363296643363697544058338901584350638600066714882508337529814729763656039238846802538009253136608863924343612977335550386006668395140745571171651486637423179504900000000000000240168354000000000000000000
Rv3877 O69741004336369770043363296843363697744058339138599672803860006690375298149039238847038599308325380092703924343630003951407471561101314866374431795051000000000000000000000000000000000
Rv3883c O05461339633875043363698343362902943364407643363297443363698344058339838599673603860006751488250913752981550392388476385993090253800933313660895392434369297733564383309589386006678395140753156110191486637503179505744906600237877365312163979322499228800000000000000000000000000000




Table2: Secretory proteins

idM africanum GM041182M canettii CIPT 140010059 3861M canettii CIPT 140010059M canettii CIPT 140060008M canettii CIPT 140070008M canettii CIPT 140070010M canettii CIPT 140070017Mtb 7199-99Mtb CCDC5079Mtb CDC 1551Mtb CTRI-2Mtb F11Mtb KZN 4207-3996Mtb KZN 4207Mtb UT205Mtb CCDC5180Mtb KZN 1435Mtb KZN V2475Mtb KZN 605Mtb KZN R506Mtb RGTB327Mtb RGTB423Mtb H37Rv broadMtb H37RvMtb H37RaM bovis AF2122 97M bovis BCG str KoreaM bovis BCG str MexicoM bovis BCG str Pasteur 1173P2M bovis BCG str Tokyo 172M abscessus ATCC 19977M avium 104M avium K-10M chubuense NBB4M gilvum PYR-GCKM gilvum Spyr1M indicus prani MTCC 9506M intracellulare ATCC 13950M intracellulare MOTT-02M intracellulare MOTT-64M kansasii ATCC 12478M leprae Br4923M leprae TNM liflandiii 128FXTM marinumM massiliense GO 06M rhodesiae NBB3M smegmatis JS623M smegmatis MC2 155M smegmatis MKD8M smegmatis str MC2 155M smegmatis str MC2 155 secondM ulcerans Agy99M vanbaalenii PYR-1Mycobacterium sp JDM601Mycobacterium sp JLSMycobacterium sp KMSMycobacterium sp MCSMycobacterium sp MOTT36Y
O69732 ESPH MYCTUESX-1secretion-ass0043363696743362901304336329584336369674405833813859967180386000659148825075375298139297636552392388460385993075253800917313660878392434353297733547383309578386006662395140737156110031486637343179504144906599237877364512163978522499228000000000000000000000000000000
P96210 ESPG1 MYCTUESX-1secretion-as339633859340628838004336440580433636966440583380385996717038600065814882507437529813803923884593859930742538009163136608773924343522977335463833095773860066610156110021486637333179504044906599137877364412163978422499227900000000000000000000000000000
P9WHW9 PPE68 MYCTUUncharacterizedPP0043363697343362901904336329644336369734405833873859967251584350438600066514882508137529814529763655839238846602538009233136608843924343592977335533833095833860066663951407435711716414866374031795047000000000000000000000000000000000
P9WIG7 PE35 MYCTUUncharacterizedPE339633865340628844004336440640433636972440583386003860006641488250803752981440392388465025380092231366088339243435829773355238330958238600666505711716314866373931795046000000000000000000000000000000000
P9WJC1 ESPK MYCTUESX-1secretion-ass00000004405833930158435103860006711488250873752981510392388472025380092903924343650003951407491561101514866374631795053000000000000000000000000000000000
P9WJC3 ESPJ MYCTUESX-1secretion-ass339633871340628850043362902343364407004336369784405833923859967291584350938600067014882508637529815029763656439238847138599308425380092831366089039243436429773355938330958738600667201561101414866374531795052000000000000000000000000000000000
P9WJD1 ESPF MYCTUESX-1secretion-ass004336369654336290110433632956433636965440583379385996716158434973860006571488250733752981372976365503923884583859930732538009153136608763924343512977335453833095760395140735156110011486637323179503944906599037877364312163978322499227800000000000000000000000000000
P9WJD3 ESPE MYCTUESX-1secretion-ass33963385734062883600433644056043363696444058337801584349638600065614882507237529813603923884573859930722538009140392434350003860066590156110001486637313179503844906598937877364212163978222499227700000000000000000000000000000
P9WJD7 ESPC MYCTUESX-1secretion-ass034062858043363671900043363671944058312338599647615843225386000401148824819375297878039238820638599283925380065331366061239243409029773328138330934200156107511486634783179479144906572837877339512163953422499203100000000000000000000000000000
P9WJE1 ESPA MYCTUESX-1secretion-ass33963361500043364380443363270843363672044058312438599647715843226386000402148824820375297879297636288392388207385992840253800654313660613392434091297733282383309343386006432395140475156107521486634793179479244906572937877339612163953522499203200000000000000000000000000000
P9WJE9 ECCE1 MYCTUESX-1secretionsy0340628854000043363698244058339738599673515843514386000674148825090375298154297636568392388475385993089253800932313660894392434368297733563000156110181486637493179505644906600137877365212163979222499228700000000000000000000000000000
P9WNB1 ECC1B MYCTUESX-1secretionsy00433636971433629017043363296243363697144058338538599672415843502386000663148825079375298143297636556392388464385993079253800921313660882392434357297733551003951407411561100714866373831795045000000000000000000000000000000000
P9WNB3 ECC1A MYCTUESX-1secretionsy3396338633406288420043364406204336369704405833843859967231584350038600066214882507837529814203923884633859930782538009203136608813924343562977335503833095813860066640156110061486637373179504444906599537877364812163978822499228300000000000000000000000000000
P9WNK5 ESXB MYCTUESAT-6-likeprotein33963386734062884600433644066043363697444058338838599672615843505386000666148825082375298146039238846738599308125380092431366088539243436029773355438330958438600666701561101014866374131795048000000000000002401683530044349345918398542000000000000000
P9WNK7 ESXA MYCTU6kDaearlysecreto00433636975433629021043363296643363697544058338901584350638600066714882508337529814729763656039238846802538009253136608863924343612977335550386006668395140745571171651486637423179504900000000000000240168354000000000000000000
P9WNQ7 ECCD1 MYCTUESX-1secretionsy004336369770043363296843363697744058339138599672803860006690375298149039238847038599308325380092703924343630003951407471561101314866374431795051000000000000000000000000000000000
P9WNR7 ECCB1 MYCTUESX-1secretionsy0043363696943362901504336329604336369694405833830158434993860006611488250773752981412976365543923884623859930772538009193136608803924343552977335490386006663395140739156110051486637363179504344906599437877364712163978722499228200000000000000000000000000000
P9WPH9 ECCA1 MYCTUESX-1secretionsy33963386134062884000433644060043363696844058338238599671915843498386000660148825076375298140039238846138599307625380091831366087939243435429773354838330957900156110041486637353179504244906599337877364612163978622499228100000000000000000000000000000
O05461 O05461 MYCTUMembrane-anchored339633875043363698343362902943364407643363297443363698344058339838599673603860006751488250913752981550392388476385993090253800933313660895392434369297733564383309589386006678395140753156110191486637503179505744906600237877365312163979322499228800000000000000000000000000000
Q79FE1 Q79FE1 MYCTUPPEfamilyprotei339632457340627443433635513043364262943363154843363551344058190738599537203859992111488236333752957532976350383923870703859917512537984903136593653924319602977320303833082153860053443951392365711698814866226531793610037877216412163831222499080600000000000000000000000000000




Table3: Region of Genetic variance

gene idM africanum GM041182M canettii CIPT 140010059 3861M canettii CIPT 140010059M canettii CIPT 140060008M canettii CIPT 140070008M canettii CIPT 140070010M canettii CIPT 140070017Mtb 7199-99Mtb CCDC5079Mtb CDC 1551Mtb CTRI-2Mtb F11Mtb KZN 4207-3996Mtb KZN 4207Mtb UT205Mtb CCDC5180Mtb KZN 1435Mtb KZN V2475Mtb KZN 605Mtb KZN R506Mtb RGTB327Mtb RGTB423Mtb H37Rv broadMtb H37RvMtb H37RaM bovis AF2122 97M bovis BCG str KoreaM bovis BCG str MexicoM bovis BCG str Pasteur 1173P2M bovis BCG str Tokyo 172M abscessus ATCC 19977M avium 104M avium K-10M chubuense NBB4M gilvum PYR-GCKM gilvum Spyr1M indicus prani MTCC 9506M intracellulare ATCC 13950M intracellulare MOTT-02M intracellulare MOTT-64M kansasii ATCC 12478M leprae Br4923M leprae TNM liflandiii 128FXTM marinumM massiliense GO 06M rhodesiae NBB3M smegmatis JS623M smegmatis MC2 155M smegmatis MKD8M smegmatis str MC2 155M smegmatis str MC2 155 secondM ulcerans Agy99M vanbaalenii PYR-1Mycobacterium sp JDM601Mycobacterium sp JLSMycobacterium sp KMSMycobacterium sp MCSMycobacterium sp MOTT36Y
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156088363396317523406267034336347484336267914336418354336307914336347484405811663859946981584115538599847314882290437529651129763425039238637038599109225379926431365856939243272229773123700395138460156088361486614953179288444906375837877143912163760522499008000000000000000000000000000000
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15610990034062882643363695543362900104336329464336369554405833683859967051584348538600064603752981272976365403923884483859930642538009053136608663924343412977335350386006651395140723156109901486637223179502844906597837877363512163977222499226700000000000000000000000000000
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1561102403406288600000433636988440583404385996741158435193860006801488250963752981602976365743923884813859930952538009383136609003924343742977335693833095933860066820156110241486637550000000000000000000000000000000000