Database Statistics

1.Total Number of non-redundant genes and references in CCDB

Total No. of Genes

Total No. of References

537

192

2.Aberrant Biological Process in which cervical cancer genes are indulged as per literature.

3.Gene Ontology Classification


a)Molecular Class

b)Molecular Function

c)Biological Process

4.Chromosome wise classification of genes

Chromosome

Number of non-redundant Genes

Gene Name

Chromosome 1 48 AIM2, BAT2L2, CACYBP, CDA, CELA2A, CR1, CRABP2, CRCT1, CRNN, CSF-1, CTSS, CYR61, DAP3, DDOST, DTL, E2F2, EDN2, EFNA1, EXO1, HIST2H2BE, IER5, IFI16, IFI6, IL10, ILF2, IVL, JAK1, KCNC4, KIAA1324, LMX1A, MUL1, MYCL1, NRAS, PTGS2, RGS1, RUNX3, S100A10, S100A7, S100A8, S100A9, SFN, SPRR1A, SPRR1B, SPRR2A, SPRR2B, SPRR3, TGFB2, TP73  
Chromosome 12

43

A2M, CAMKK2, CCND2, CD63, CDK2, CDKN1B, CHFR, CLEC2B, DDIT3, EMP1, ENDOU, EPS8, GAPDH, GLI1, GLTP, GYS2, HOXC10, HSPB8, IFNG, IGF1, IGFBP6, KITLG, KRAS, KRT1, KRT18, KRT3, KRT4, KRT6B, KRT7, KRT8, LGR5, MDM2, NTF3, NTN4, OAS3, P2RX4, PA2G4, PEBP1, POP5, RAPGEF3, RARG, TBX3, VWF  
Chromosome 11

42

APLP2, BANF1, CADM1, CALCA, CCND1, CD44, CRYAB, CTSC, CTSF, FANCF, GSTP1, HRAS, HSPB2, IFITM1, IGF2, IL18, LDHA, MAP3K11, MMP1, MMP10, MMP12, MMP13, MMP3, MRPL11, MYOD1, ORAOV1, PGR, POU2F3, PPP2R1B, RARRES3, RTN3, SAA1, SIPA1, SLC3A2, SPA17, ST14, STARD10, TMEM132A, TRIM29, VEGFB, WT1, YIF1A  
Chromosome 5

34

ALDH7A1, APC, BASP1, BRD9, BXDC2, C5orf22, C5orf28, CCNB1, CSF1R, DHFR, DUSP1, FASTKD3 , FGF1, GPX3, HIN-1, ITGA1, NDUFS6, NNT, OSMR, PAIP1, PAPD7, PTTG1, RNASEN, RPL37, SCAMP1, SDHA, SEPP1, SKP2, SPARC, SPINK5, TARS, TERT, TMCO6, TRIP13  
Chromosome 17

34

ACADVL, ALOX12, ALOX12B, BIRC5, BRCA1, C1QBP, COL1A1, CUEDC1, ERBB2, GRB2, HIC1, HOXB6, KRT10, KRT13, KRT15, KRT17, KRT19, KRTHA3B, LSMD1, MRPS23, NME1, NME2, NPTX1, PDK2, PECAM1, PHB, PRR11, RARA, STAT3, TIMP2, TMC6, TOB1, TOP2A, TP53  
Chromosome 20

34

ADRM1, AHCY, ASXL1, ATP9A, B4GALT5, BCL2L1, C20orf20, C20orf30, CDH4, CEBPB, CSE1L, DDX27, E2F1, EDN3, GSS, LAMA5, MMP9, PAX1, PCNA, PIGT, POFUT1, PTK6, RALY, RBL1, RNF114, SEMG2, STAU1, STX16, SYCP2, TCEA2, TGM3, THBD, TPX2, ZNF217  
Chromosome 6

31

CD83, CDC40, CDKN1A, CITED2, CRISP3, CTGF, DEK, E2F3, EDN1, ESR1, GJA1 , GRM4, GTF2H4, HIST1H1C, HLA-C, HLA-DQB1, HLA-DRA, HLA-DRB3, HLA-DRB5, MCM3, ME1, MLLT4, NOL7, NRM, PLAGL1, PSMB9, THBS2, TNF, TREM2, TUBB2, VEGFA  
Chromosome 2

30

ANXA4, ATIC, CD28, CXCR2, EPCAM, ERBB4, HDLBP, HSPD1, ICOS, IGFBP2, IGFBP5, IL1A, IL1RN, ITGA4, ITGA6, ITGAV , ITM2C, MAL, MSH2, MYCN, NCL, OSR1, PDCD1, PIGF, RPRM , RRM2, SDC1 , SP100, STAT1, TGFA  
Chromosome 16

28

CDH1, CDH11, CDH13, CDH15, CDH3, CES1, CNOT1, CYBA, E2F4, FANCA, FUS, GFOD2, HBA2, HS3ST2, IL32, MMP2, MSLN, MT1G, NAE1, NDRG4, NQO1, PPL, PYCARD, RBL2, RRAD, SLC7A6OS, SOCS1, VPS35  
Chromosome 19

28

APOC1, BST2, C3, CCNE1, CEACAM1, CEACAM5, CEACAM6, CEACAM7, DNMT1, GDF15, IRF3, JUNB, KLK10, KLK11, KLK12, KLK13, KLK2, KLK7, KLK8, LGALS7, RPS19, RRAS, STK11, SULT2B1, TGFB1, TYK2, UPK1A, XRCC1  
Chromosome 3

27

APOD, BLU, CAMKV, CCR2, CLDN1, CTNNB1, ECT2, FHIT, FOXL2, HLTF, HYAL1, LHFPL4, LSM3, MCM2, MLH1, PCNP, PLOD2, PLSCR1, RAF1, RARB, RASSF1, RBP1, RPL39L, RPSA, TFRC, VHL, ZBED2  
Chromosome 4

26

C4orf41, CPE, CWH43, EDNRA, EREG, FGF2 , HOPX, HPGD, IL8, KIT, KLF3, LARP7, MSX1, NEK1, NKX6-1, PCDH10, PDGFRA, PRDM5, S100P, SFRP2, SPP1, TBC1D1, TLR2, TMPRSS11D, TMPRSS11E, VEGFC  
Chromosome 7

19

AEBP1, ANLN, BRAF, BZW2, CDK6, EGFR, EZH2, GARS, HOXA1, IGFBP3, IL6, ITGB8, MET, PRSS2, SFRP4, STK31, TFPI2, TRA2A, TWIST1  
Chromosome 9

19

ANXA1, AQP3, BAG1, BICD2, CDKN2A, CDKN2B, CKS2, CLIC3, CTSL1, DAPK1, ENG, EPB41L4B , INPP5E, MRPS2, PRSS3, RCL1, SYK, TGFBR1, TLR4  
Chromosome 10

16

ANXA8, ARHGAP12, BNIP3, CPEB3, DNAJC9, FGFR2, GATA3, ITGB1, MGMT, NEBL, OAT, PDCD4, PPP1R3C, PTEN, SCD, SFRP5  
Chromosome 8

14

ADAM9, DLC1, DUSP26, E2F5, LY6D, LYPLA1, MCM4, MYC, NDRG1, PLAT, SFRP1, SLURP1, SULF1, TNFRSF10C  
Chromosome 15

13

ANXA2, C15orf48, CPEB1, CTSH, DUT, FGF7, IMP3, MEF2A, ONECUT1, PDIA3, RHCG, THBS1, TSPAN3  
Chromosome 13

10

C13ORF18, CCNA1, FLT1, GTF2F2, HMGB1, IPO5, MBNL2, PTPN6, SCEL, SOX1  
Chromosome 18

10

BCL2, CDH2, DSG1, DSG2, EPB41L3, NOL4, SERPINB5, SMAD2, SMAD4, TYMS  
Chromosome 22

10

APOL2, ARHGAP8, CELSR1, DMC1, KCNJ4, MCM5, MMP11, MYH9, TIMP3, UFD1L  
Chromosome 14

8

AKT1, ANG, BCL2L2, ESR2, HSP90AA1, MMP14, SERPINA3, SIX1  
Chromosome X

8

FLNA, HUWE1, MSN, PLP2, TIMP1, TKTL1, TLR8, VSIG4  
Chromosome 21

5

DNMT3L, ITGB2, PWP2H, RUNX1, TFF3  

5.Comparison with other cancer databases

Name of Databases   Number of common genes   Number of unique genes  
Lung Cancer Database (HLungDB)

293 (Genes confirmed in Lung Cancer)

244

Human Prostate Gene Database (HPGD)  

35

502

Network of Cancer Genes (NCGs)

61

476

Dragon Database of Genes Implicated in Esophageal Cancer (DDEC)  

105

432

Dragon Database for Exploration of Ovarian Cancer Genes (DDOC)

70

467


6.Conservation pattern of 537 genes according to Homologene Database.